Dr. Louis Siminovitch,
Chair in Research
A scientific visionary who, as founding director of the Lunenfeld-Tanenbaum Research Institute, built the top-ranked biomedical research institute in Canada.
Dr. Louis Siminovitch,
Chair in Research
A scientific visionary who, as founding director of the Lunenfeld-Tanenbaum Research Institute, built the top-ranked biomedical research institute in Canada.
Dr. Louis Siminovitch,
Chair in Research
A scientific visionary who, as founding director of the Lunenfeld-Tanenbaum Research Institute, built the top-ranked biomedical research institute in Canada.

Louis “Lou” Siminovitch was the first chair of what is today the department of molecular genetics in the Temerty Faculty of Medicine and the founding director of the Lunenfeld-Tanenbaum Research Institute (LTRI) at Sinai Health.

As a molecular biologist and pioneer in human genetics, Siminovitch made important contributions in the fields of bacterial and animal virus genetics, human genetics and cancer research, publishing more than 200 papers.

His work helped uncover the genetic bases of muscular dystrophy and cystic fibrosis, and it laid the groundwork for genetic connections to cancer. 

He contributed to the Nobel Prize-winning work in molecular genetics of Jacques Monod and Andre Lwoff during his years at the Pasteur Institute in Paris. He was an inductee in the Canadian Medical Hall of Fame, and an Officer and Companion of the Order of Canada. 

Siminovitch was renowned as a mentor and researcher, but also as a scientific builder. He played key roles in establishing and developing several top research environments in Canada, including the Ontario Cancer Institute at Princess Margaret Hospital and The Hospital for Sick Children Research Institute. 

At age 65, when others might have contemplated retirement, Siminovitch was at the top of his game. Mount Sinai recruited him to build an academic research institute, and as inaugural director he attracted 25 of the globe’s most eminent scientists to the team. Thanks to his foundational efforts, LTRI is today the top-ranked biomedical research institute in Canada.

Louis “Lou” Siminovitch was the first chair of what is today the department of molecular genetics in the Temerty Faculty of Medicine and the founding director of the Lunenfeld-Tanenbaum Research Institute (LTRI) at Sinai Health.

As a molecular biologist and pioneer in human genetics, Siminovitch made important contributions in the fields of bacterial and animal virus genetics, human genetics and cancer research, publishing more than 200 papers.

His work helped uncover the genetic bases of muscular dystrophy and cystic fibrosis, and it laid the groundwork for genetic connections to cancer. 

He contributed to the Nobel Prize-winning work in molecular genetics of Jacques Monod and Andre Lwoff during his years at the Pasteur Institute in Paris. He was an inductee in the Canadian Medical Hall of Fame, and an Officer and Companion of the Order of Canada. 

Siminovitch was renowned as a mentor and researcher, but also as a scientific builder. He played key roles in establishing and developing several top research environments in Canada, including the Ontario Cancer Institute at Princess Margaret Hospital and The Hospital for Sick Children Research Institute. 

At age 65, when others might have contemplated retirement, Siminovitch was at the top of his game. Mount Sinai recruited him to build an academic research institute, and as inaugural director he attracted 25 of the globe’s most eminent scientists to the team. Thanks to his foundational efforts, LTRI is today the top-ranked biomedical research institute in Canada.

Louis “Lou” Siminovitch was the first chair of what is today the department of molecular genetics in the Temerty Faculty of Medicine and the founding director of the Lunenfeld-Tanenbaum Research Institute (LTRI) at Sinai Health.

As a molecular biologist and pioneer in human genetics, Siminovitch made important contributions in the fields of bacterial and animal virus genetics, human genetics and cancer research, publishing more than 200 papers.

His work helped uncover the genetic bases of muscular dystrophy and cystic fibrosis, and it laid the groundwork for genetic connections to cancer. 

He contributed to the Nobel Prize-winning work in molecular genetics of Jacques Monod and Andre Lwoff during his years at the Pasteur Institute in Paris. He was an inductee in the Canadian Medical Hall of Fame, and an Officer and Companion of the Order of Canada. 

Siminovitch was renowned as a mentor and researcher, but also as a scientific builder. He played key roles in establishing and developing several top research environments in Canada, including the Ontario Cancer Institute at Princess Margaret Hospital and The Hospital for Sick Children Research Institute. 

At age 65, when others might have contemplated retirement, Siminovitch was at the top of his game. Mount Sinai recruited him to build an academic research institute, and as inaugural director he attracted 25 of the globe’s most eminent scientists to the team. Thanks to his foundational efforts, LTRI is today the top-ranked biomedical research institute in Canada.

He was relentless in his pursuit of research excellence, with an inspiring commitment to mentoring generations of scientists and leading scientific communities.

Leah Cowen, Vice-President, Research, Innovation & Strategic Initiatives, University of Toronto,
and former chair of molecular genetics at U of T

About Mount Sinai 100 Chairs

In 2023, Mount Sinai Hospital will mark its 100th anniversary. To honour the physicians and scientists who have made breakthrough discoveries and whose achievements have elevated Sinai Health’s reputation for world-class care, we are pleased to introduce our Mount Sinai 100 Chairs. These legacy chairs carry the names of Sinai Health’s most eminent trailblazers and will help recruit and fund the work of a new generation of clinicians and scientists, securing the next century of caring at Sinai Health. We invite you to help us imagine the next 100 years.

About Mount Sinai 100 Chairs

In 2023, Mount Sinai Hospital will mark its 100th anniversary. To honour the physicians and scientists who have made breakthrough discoveries and whose achievements have elevated Sinai Health’s reputation for world-class care, we are pleased to introduce our Mount Sinai 100 Chairs. These legacy chairs carry the names of Sinai Health’s most eminent trailblazers and will help recruit and fund the work of a new generation of clinicians and scientists, securing the next century of caring at Sinai Health. We invite you to help us imagine the next 100 years.

About Mount Sinai 100 Chairs

In 2023, Mount Sinai Hospital will mark its 100th anniversary. To honour the physicians and scientists who have made breakthrough discoveries and whose achievements have elevated Sinai Health’s reputation for world-class care, we are pleased to introduce our Mount Sinai 100 Chairs. These legacy chairs carry the names of Sinai Health’s most eminent trailblazers and will help recruit and fund the work of a new generation of clinicians and scientists, securing the next century of caring at Sinai Health. We invite you to help us imagine the next 100 years.

Help Sinai Health secure the future of world-class care for the next 100 years by supporting our Mount Sinai 100 Chairs.
Help Sinai Health secure the future of world-class care for the next 100 years by supporting our Mount Sinai 100 Chairs.
Help Sinai Health secure the future of world-class care for the next 100 years by supporting our Mount Sinai 100 Chairs.